期刊
CURRENT OPINION IN NEUROBIOLOGY
卷 31, 期 -, 页码 111-118出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2014.09.004
关键词
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资金
- Wellcome Trust/DBT India Alliance [500145/Z/09/Z]
- DBT-IISc Partnership programme
Brain signals often show fluctuations in particular frequency bands, which are highly conserved across species and are associated with specific behavioural states. Such rhythmic patterns can be captured in the local field potential (LFP), which is obtained by low-pass filtering the extracellular signal recorded from microelectrodes. However, LFP also captures other neural processes that are associated with spikes, such as synaptic events preceding a spike, low-frequency component of the action potential (spike bleed-through) and spike afterhyperpolarization, which pose difficulties in the estimation of the amplitude and phase of the rhythm with respect to spikes. Here we discuss these issues and different techniques that have been used to dissociate the rhythm from other neural events in the LFP.
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