期刊
CRITICAL CARE
卷 24, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s13054-020-03166-0
关键词
-
资金
- Vidi grant of the Netherlands Association for Scientific Research
- ERC [833247]
- Spinoza Grant of the Netherlands Association for Scientific Research
- European Research Council (ERC) [833247] Funding Source: European Research Council (ERC)
COVID-19 is an emerging disease that can manifest itself as asymptomatic or mild respiratory tract infection in the majority of individuals, but in some, it can progress into severe pneumonia and acute respiratory distress syndrome (ARDS). Inflammation is known to play a crucial role in the pathogenesis of severe infections and ARDS and evidence is emerging that the IL-1/IL-6 pathway is highly upregulated in patients with severe disease. These findings open new avenues for host-directed therapies in patients with symptomatic SARS-CoV-2 infection and might in addition to antiviral treatment be enough to curb the currently unacceptably high morbidity and mortality associated with COVID-19.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据