期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 18, 期 26, 页码 4916-4921出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ob00629g
关键词
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资金
- CAPES [001]
- CNPq
- CERSusChem GSK/FAPESP [2014/50249-8]
- INCT-Catalise
- FAPESC-Pronex
- CNPq [433896/2018-3]
Herein, we report an eco-friendly, electrosynthetic approach for the intramolecular oxyselenylation of allyl-naphthol/phenol derivatives. This reaction proceeds with 0.2 equiv. of (Bu4NClO4)-Bu-n as an electrolyte and Pt working electrodes in an undivided cell, resulting in the selenyl-dihydrofurans in good to excellent yields. Furthermore, several of the synthesized products presented a high percentage of acetylcholinesterase (AChE) inhibition, highlighting their potential anti-Alzheimer activity.
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