期刊
ORGANIC CHEMISTRY FRONTIERS
卷 7, 期 14, 页码 1948-1969出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0qo00397b
关键词
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资金
- National Natural Science Foundation of China [21901184, 21572160, 21702091]
- Science & Technology Development Fund of Tianjin Education Commission for Higher Education [2018KJ159]
- Doctoral Program Foundation of Tianjin Normal University [043135202-XB1703]
- Program for Innovative Research Team in University of Tianjin [TD13-5074]
Cyclization/functionalization of unsaturated oxime esters (ethers) is a powerful strategy for the synthesis of versatile functionalized nitrogen-containing scaffolds, which are valuable structural motifs in numerous bioactive molecules. This review provides an overview of the recent advances in cascade cyclization of unsaturated oxime esters (ethers) with different functional group reagents. Typical examples are listed and mechanistic aspects are discussed in detail. Moreover, the remaining challenges and future perspectives are presented at the end.
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