期刊
CHEMICAL COMMUNICATIONS
卷 56, 期 56, 页码 7753-7756出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc00165a
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资金
- National Natural Key R&D Program of China [2017YFA0205400]
- National Natural Science Foundation of China [81603043, 31872755, 81872811]
- Central Fundamental Research Funds for the Central Universities
We utilized albumin as a reducing agent to establish novel copper-based and pH-sensitive nanocarrier CuNPs with abundant Cu+, which can encapsulate histone deacetylase (HDAC) inhibitor vorinostat to form uniform and stable nanomedicine V-CuNPs for synergistic chromatin remodelling and chemodynamic therapy.
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