期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 33, 期 -, 页码 1-9出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2015.06.004
关键词
-
资金
- National Institutes of Health [RO1 HL119476, RO1 CA160433]
- Commonwealth Foundation
- Flight Attendants Medical Research Institute
- NATIONAL CANCER INSTITUTE [R01CA160433] Funding Source: NIH RePORTER
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R01HL119476] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [T32GM007309] Funding Source: NIH RePORTER
Recent advances have defined a role for abnormally short telomeres in a broad spectrum of genetic disorders. They include rare conditions such as dyskeratosis congenita as well pulmonary fibrosis and emphysema. Now, there is new evidence that some familial cancers, such as melanoma, are caused by mutations that lengthen telomeres. Here, we examine the significance of these short and long telomere length extremes for understanding the molecular basis of age-related disease and cancer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据