期刊
CHEMICAL PAPERS
卷 74, 期 12, 页码 4593-4598出版社
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/s11696-020-01287-y
关键词
Hiyama coupling; Ionic liquids; Homogeneous catalysis; Green chemistry
资金
- Budapest University of Technology and Economics
- National Research, Development and Innovation Office [KH 129508]
- Higher Education Excellence Program of the Ministry of Human Capacities of Budapest University of Technology and Economics (BME FIKP-BIO)
The introduction of a biomass-derived ionic liquid into the Hiyama coupling reactions, which has been considered as a powerful tool for the synthesis of symmetrically and non-symmetrically substituted biaryl structures, could further control or even reduce the environmental impact of this transformation. It was shown that tetrabutylphosphonium 4-ethoxyvalerate, a gamma-valerolactone-based ionic liquid, can be utilized as an alternative solvent to create carbon-carbon bonds between aryl iodides and functionalized organosilanes in the presence of 1 mol% Pd under typical Hiyama conditions (130 degrees C, 24 h, tetrabutylammonium fluoride activator). A comparison of different ionic liquids was performed, and the effects of the catalyst precursor and the moisture content of the reaction mixture on the activity of the catalyst system were investigated. The functional group tolerance was also studied, resulting in 15 cross-coupling products (3a-o) with isolated yields of 45-72% and excellent purity (> 98%).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据