4.5 Article

Recycling endosomes

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CURRENT OPINION IN CELL BIOLOGY
卷 35, 期 -, 页码 117-122

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CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2015.04.018

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  1. NIH [RO1 DK48370, RO1 DK070856]
  2. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK048370, R01DK070856] Funding Source: NIH RePORTER

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The endosomal membrane recycling system represents a dynamic conduit for sorting and re-exporting internalized membrane constituents. The recycling system is composed of multiple tubulovesicular recycling pathways that likely confer distinct trafficking pathways for individual cargoes. In addition, elements of the recycling system are responsible for assembly and maintenance of apical membrane specializations including primary cilia and apical microvilli. The existence of multiple intersecting and diverging recycling tracks likely accounts for specificity in plasma membrane recycling trafficking.

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