期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 36, 期 -, 页码 40-49出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2015.08.008
关键词
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资金
- National Science Foundation [DGE1144152]
- Department of Energy [DE-SC0012658]
- MIT Media Lab
- Wyss Institute for Biologically Inspired Engineering
- SynBERC
- U.S. Department of Energy (DOE) [DE-SC0012658] Funding Source: U.S. Department of Energy (DOE)
Symbioses provide a way to surpass the limitations of individual microbes. Natural communities exemplify this in symbioses like lichens and biofilms that are robust to perturbations, an essential feature in fluctuating environments. Metabolic capabilities also expand in consortia enabling the division of labor across organisms as seen in photosynthetic and methanogenic communities. In engineered consortia, the external environment provides levers of control for microbes repurposed from nature or engineered to interact through synthetic biology. Consortia have successfully been applied to real-world problems including remediation and energy, however there are still fundamental questions to be answered. It is clear that continued study is necessary for the understanding and engineering of microbial systems that are more than the sum of their parts.
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