期刊
PSYCHOLOGICAL SCIENCE
卷 31, 期 8, 页码 1025-1035出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0956797620938160
关键词
heritability; genomic structural equation modeling; self-control; UPPS-P Impulsive Behavior Scale; Barratt Impulsiveness Scale; open data; open materials
资金
- National Institutes of Health (NIH) [DC016977, HD098859]
- NIH [MH063207, DA046064, DA046413, DA042742]
- NARSAD Young Investigator Award from the Brain & Behavior Research Foundation [27676]
- California Tobacco-Related Disease Research Program (TRDRP) [28IR-0070, T29KT0526]
Factor analyses suggest that impulsivity traits that capture tendencies to act prematurely or take risks tap partially distinct constructs. We applied genomic structure equation modeling to evaluate the genetic factor structure of two well-established impulsivity questionnaires, using published statistics from genome-wide association studies of up to 22,861 participants. We also tested the hypotheses that delay discounting would be genetically separable from other impulsivity factors and that emotionally triggered facets of impulsivity (urgency) would be those most strongly genetically correlated with an internalizing latent factor. A five-factor model best fitted the impulsivity data. Delay discounting was genetically distinct from these five factors. As expected, the two urgency subscales were most strongly related to an internalizing-psychopathology latent factor. These findings provide empirical genetic evidence that impulsivity can be broken down into distinct categories of differential relevance for internalizing psychopathology. They also demonstrate how measured genetic markers can be used to inform theories of psychology and personality.
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