期刊
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
卷 33, 期 7, 页码 961-974出版社
SPRINGER
DOI: 10.1007/s10554-017-1159-2
关键词
Fractional flow reserve; Coronary physiology; Stable angina; Myocardial infarction; Optimal medical therapy; Coronary revascularisation
资金
- British Heart Foundation (BHF) [FS/14/15/30661]
- BHF project [PG/14/97/31263]
- British Heart Foundation [FS/14/15/30661, PG/11/55/28999, PG/14/97/31263] Funding Source: researchfish
- Chest Heart and Stroke Scotland [Res11/A136] Funding Source: researchfish
- Medical Research Council [MR/N003403/1] Funding Source: researchfish
- MRC [MR/N003403/1] Funding Source: UKRI
Fractional flow reserve (FFR) is a reference invasive diagnostic test to assess the physiological significance of an epicardial coronary artery stenosis. FFR-guided percutaneous coronary intervention in stable coronary artery disease has been assessed in three seminal clinical trials and the indications for FFR assessment are expanding into other clinical scenarios. In this article we review the theoretical, experimental and clinical basis for FFR measurement. We place FFR measurement in the context of the comprehensive invasive assessment of coronary physiology in patients presenting with known or suspected angina pectoris in daily clinical practice, and review the recent developments in FFR assessment.
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