期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 101, 期 -, 页码 304-313出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2017.03.061
关键词
Carp swim bladder collagen; Collagen hydrolysates; In silico analysis; Valorization; Antioxidative collagen peptides
资金
- Department of Science and Technology (DST), New Delhi, India of DST-INSPIRE-SRF Fellowship [IF-131071]
This study explores the sustainable valorization of carp swim bladder by-products. The high-value molecule collagens were successfully extracted from carp swim bladder with a yield of 60% (dry weight basis) and characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis, UV-spectrum and Fourier transform infrared spectroscopy. The extracted collagens showed the fibril-forming ability and high denaturation temperature (38-39 degrees C). Furthermore, the extracted collagens subjected to preparing bioactive collagen hydrolysates with-potential antioxidant activities. In vitro and In silico approaches (Pep Draw, BIOPEP, PeptideRanker, Pepcalc and ToxinPred) were employed to evaluate the potential of carp collagens as a potential source of bioactive peptides. Furthermore, primary structure, biological potential, physicochemical, sensory and toxicity characteristics of the theoretically release antioxidative collagen peptides were predicted. Overall, the present study highlights the carp collagens hydrolysate could be a promising precursor of bioactive peptides for developing functional food or nutraceutical products. (C) 2017 Elsevier B.V. All rights reserved.
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