期刊
CLINICAL NUCLEAR MEDICINE
卷 45, 期 8, 页码 611-617出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000003132
关键词
PET; PET; CT; FDG; rectal neoplasm; colorectal cancer; diagnosis; surveillance; staging; restaging; response to therapy; radiotherapy planning; concurrent radiochemotherapy; neoadjuvant therapy; biological target volume; BTV; adaptive radiotherapy; locally advanced rectal cancer; LARC
At the moment, international guidelines for rectal cancer suggest to consider(18)F-FDG PET/CT scan in a few conditions: (1) at disease presentation in case of suspected or proven metastatic synchronous adenocarcinoma with potentially curable M1 disease; (2) in the recurrence workup for serial carcinoembryonic antigen level elevation; (3) in the recurrence workup with metachronous metastases documented by CT, MRI, or biopsy; (4) in case of strong contraindication to IV contrast agent administration; and (5) to evaluate an equivocal finding on a contrast-enhanced CT or MRI. PET/CT is not indicated in the follow-up or surveillance of rectal cancer. On the other hand, an attentive evaluation of the literature shows that PET/CT may also be used in some circumstances with significant levels of diagnostic accuracy. This review article aims to emphasize differences between current international guidelines and scientific literature in the role of PET/CT in rectal cancer.
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