期刊
JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY
卷 62, 期 4, 页码 438-448出版社
KOREAN SOCIETY ANIMAL SCIENCE & TECHNOLOGY
DOI: 10.5187/jast.2020.62.4.438
关键词
Korean native pig; Genomic prediction; Admixed reference; Genome-wide association study
资金
- Cooperative Research Program for Agriculture Science and Technology Development Rural Development Administration, Korea [PJ011191012017]
- Rural Development Administration (RDA), Republic of Korea [PJ011191012017] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
This study was performed to increase the accuracy of genomic estimated breeding value (GEBV) predictions for domestic pigs using single-breed and admixed reference populations (single-breed of Berkshire pigs [BS] with cross breed of Korean native pigs and Landrace pigs [CB]). The principal component analysis (PCA), linkage disequilibrium (LD), and genome-wide association study (GWAS) were performed to analyze the population structure prior to genomic prediction. Reference and test population data sets were randomly sampled 10 times each and precision accuracy was analyzed according to the size of the reference population (100, 200, 300, or 400 animals). For the BS population, prediction accuracy was higher for all economically important traits with larger reference population size. Prediction accuracy was ranged from -0.05 to 0.003, for all traits except carcass weight (CWT), when CB was used as the reference population and BS as the test. The accuracy of CB for backfat thickness (BF) and shear force (SF) using admixed population as reference increased with reference population size, while the results for CWT and muscle pH at 24 hours after slaughter (pH) were equivocal with respect to the relationship between accuracy and reference population size, although overall accuracy was similar to that using the BS as the reference.
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