期刊
RSC ADVANCES
卷 10, 期 48, 页码 28705-28710出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ra05378c
关键词
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资金
- Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi [2019L0879, 2019L0894]
- Construction Plan of 1331 engineering Photoelectric Material Innovation Team of Jinzhong University [jzxycxtd2017007]
- Shanxi 1331 project Key Innovative Research Team [PY201817]
The hydroxyl radical ((OH)-O-.) has been suggested to play very vital roles in many physiological and pathological processes. However, selective detection of (OH)-O-. is highly challenging owing to its extremely high reactivity and short lifetime. Herein, we designed and synthesized a sensitive turn on fluorescent probe for detecting endogenous (OH)-O-. based on a BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) platform. The probe had shown good properties including high sensitively, ideal selectively and low cytotoxicity, and was successfully employed to image endogenous hydroxyl radical in living cells.
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