期刊
INSECT MOLECULAR BIOLOGY
卷 27, 期 1, 页码 1-7出版社
WILEY
DOI: 10.1111/imb.12347
关键词
ionotropic receptor; taste; smell; temperature
资金
- National Research Foundation of Korea (NRF) - Basic Science Research Program of the NRF of Korea
- Ministry of Education [2014R1A1A2058094, 2016R1D1A1B03931273]
- Global Scholarship Program for Foreign Graduate Students at Kookmin University in Korea
Ionotropic receptors (IRs), which form ion channels, can be categorized into conserved antennal IRs', which define the first olfactory receptor family of insects, and species-specific divergent IRs', which are expressed in gustatory receptor neurones. These receptors are located primarily in cell bodies and dendrites, and are highly enriched in the tips of the dendritic terminals that convey sensory information to higher brain centres. Antennal IRs play important roles in odour and thermosensation, whereas divergent IRs are involved in other important biological processes such as taste sensation. Some IRs are known to play specific biological roles in the perception of various molecules; however, many of their functions have not yet been defined. Although progress has been made in this field, many functions and mechanisms of these receptors remain unknown. In this review, we provide a comprehensive summary of the current state of knowledge in this field.
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