期刊
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
卷 40, 期 -, 页码 10-17出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ifset.2016.07.030
关键词
Whey protein nanoparticles; Caffeine release; Encapsulation efficiency; Loading capacity; Nanostructures; Full factorial design
资金
- Conselleria de Cultura, Educacion e Ordenacion Universitaria (Xunta de Galicia, Spain)
- Marie Curie COFUND Postdoctoral Research Fellowship [600375]
- Fundacao para a Ciencia e a Tecnologia (FCT) [UID/BIO/04469/2013]
- COMPETE 2020 [POCI-01-0145-FEDER-006684]
- [RECI/BBB-EBI/0179/2012]
- [FCOMP-01-0124-FEDER-027462]
- Fundação para a Ciência e a Tecnologia [RECI/BBB-EBI/0179/2012] Funding Source: FCT
This work evaluated the stability and functionality of nanotubes obtained from a-lactalbumin (alpha-LA). alpha-LA nanotubes' structure was highly stable during a freeze-drying process but not after grinding. The ability of alpha-LA nanotubes to encapsulate caffeine, used as a model molecule, was evaluated. alpha-LA nanotubes were highly effective for this purpose as encapsulation efficiency (%EE) was near 100% and loading capacity (%LC) near 10% at 1.5/20 and 2/20 ratios (caffeine/alpha-LA, w/w). alpha-LA nanotubes' structure was not affected by the presence of caffeine. Also, in general, refrigeration temperatures and neutral or alkaline conditions, under which the adverse effect of chelating agents was prevented, helped to stabilise alpha-LA nanotubes' structure and maintain caffeine encapsulated. At 8 degrees C and pH 7.5, in the presence of 75 mu g mL(-1) of EDTA, >50% of the caffeine remained encapsulated into alpha-LA nanotubes. Industrial relevance: Linear and hollow structures could be highly effective to increase the viscosity while encapsulating bioactive compounds to protect them from degradation, provide on-demand release, or mask unpleasant organoleptic properties. However, until now, carbon nanotubes are the most commonly used carriers for the controlled release of bioactive molecules and these are not food-grade materials. Enzymatic partial hydrolysis of alpha-lactalbumin (alpha-LA) in the presence of a divalent ion results in the formation of food-grade nanotubes with high potential in the food and cosmetic industry. In this work the functionality of alpha-LA nanotubes was evaluated considering their applicability in real food. (C) 2016 Elsevier Ltd. All rights reserved.
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