期刊
MOLECULAR GENETICS MICROBIOLOGY AND VIROLOGY
卷 35, 期 2, 页码 61-68出版社
ALLERTON PRESS INC
DOI: 10.3103/S0891416820020056
关键词
BMP-2; Escherichia coli; bone tissue regeneration; osteoplastic materials; review
资金
- Russian Science Foundation [16-15-00133]
- Russian Science Foundation [16-15-00133] Funding Source: Russian Science Foundation
This review is devoted to current approaches to the combined use of BMP-2 with other protein factors to increase osteoinductivity of recently developed materials. The current trend is to create materials with a low BMP-2 concentration that are efficient in osteoinduction and provide continuous protein release. A number of medications have been developed in Russia and South Korea on the basis of BMP-2 synthesized inE. colicells. The first experience of their use in orthopedics, traumatology, spinal surgery, and dental implantology showed promising results. Also, the possibility of the recombinant BMP-2 use in ophthalmology, and oncology, as well as osteoarthritis treatment, was studied. The databases of PubMed Central (U.S. National Institutes of Health's National Library of Medicine (NIH/NLM)), PubMed (NLM National Center for Biotechnology Information (NCBI)), and e-library (Science Electronic Library) were used to analyze published results.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据