期刊
CURRENT CANCER DRUG TARGETS
卷 15, 期 4, 页码 337-351出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1568009615666150211104524
关键词
Cell penetrating peptides; tumor; targeting
类别
Cell-penetrating peptides (CPPs) have been previously shown to be powerful transport vector tools for the delivery of a large variety of cargoes through the cell membrane, as well as other physiological membranes. And since they're relatively cell-, receptor-and energy-independent, CPPs have unique advantages in facilitating drugs entry into cells. This paper briefly reviews the discovery, mechanism and classification of CPPs, and especially focuses on the specific limitations of CPPs and their potential applications for tumor-targeted delivery of biologically active molecules, imaging agents and carriers.
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