期刊
ADVANCES IN NATURAL SCIENCES-NANOSCIENCE AND NANOTECHNOLOGY
卷 11, 期 3, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/2043-6254/ab9f2b
关键词
gold nanoparticles; green synthesis; catalysis; environmental mitigation; cytotoxicity
Plant extracts of amla (Phyllanthus emblica), tea (Camellia sinensis) and coffee (Coffea) are prepared and used for the green synthesis of stable gold nanoparticles. The approach is simple, cost effective and environmentally friendly. The various gold nanoparticles (AuNPs-Amla, AuNPs-Tea and AuNPs-Coffee) are characterised by various spectroscopic and microscopic techniques. The borohydride mediated reduction of 4-nitrophenol is used as a model system to study the catalytic activity of the resulting AuNPs. The reaction rates are quite high following the first order kinetics with first order rate constant of 5.4 x 10(-1)min(-1), 8.7 x 10(-1)min(-1), and 2.8 x 10(-1)min(-1)respectively for AuNP-amla, AuNP-tea and AuNP-coffee. Thein vitrocytotoxicity study by MTT assay reveals that the various green synthesised AuNPs are not cytotoxic to living cells and their IC(50)values towards two cancer cell lines, MCF-7 and HCT-116 are within the permissible doses. Moreover, IC(50)values for AuNPs are in good agreement with direct treatment of aqueous plant extracts.
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