4.1 Article Data Paper

Freezing activity brief data from a new FUS mutant zebrafish line

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DATA IN BRIEF
卷 31, 期 -, 页码 -

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ELSEVIER
DOI: 10.1016/j.dib.2020.105921

关键词

Zebrafish (Danio Rerio); FUS KO model; Visual stimulation with the automatized; viewpoint zebrabox system; Freezing response; Behaviour

资金

  1. ERC Consolidator Grant
  2. AFM-Telethon
  3. Association pour la Recherche sur la Sclerose Laterale Amyotrophique (ARSLA)

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The data presented in this paper are related to the research article Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS. In this model the lack of fus causes reduced lifespan as well as impaired motor abilities associated with a decrease of motor neurons axons lenght and an increase of neuromuscular junctions fragmentation. Data in this article describes the global locomotor activity data at 3, 4 and 5 days post fertilization in WT, fus heterozygous (fus(+/-)) and fus homozygous (fus(-/-)) zebrafish embryos as a response to visual light stimulation, with particular attention on the freezing respose. (c) 2020 Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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