期刊
CHEMICAL SOCIETY REVIEWS
卷 49, 期 19, 页码 6800-6815出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cs00348d
关键词
-
资金
- National Natural Science Foundation of China [21925802, 21878039, 21822804, 21421005]
- NSFC-Liaoning United Fund [U1608222, U1908202]
- Nanyang Technological University [M4081627]
- Singapore Ministry of Education [2017-T1-002-134-RG147/17, MOE2016-T2-1-098]
Chemiluminescence, the generation of Eight through chemiexcitation as a result of chemical reactions, has emerged as a novel tool for bioimaging and therapy in vivo. Due to the elimination of external optical excitation, it can effectively avoid background autofluorescence existing in fluorescence techniques, providing extremely high signal-to-noise ratios and sensitivity in bioimaging. Furthermore, in situ emitted photons can replace traditional excitation Eight to construct chemiexcited photodynamic therapy or drug release systems for the monitoring and treatment of deeply seated diseases or tumors. In this tutorial review, we will focus on the recent advancements of chemiluminescent platforms based on Euminophore substrates including luminol and its derivatives, cypridina luciferin analogs, peroxyoxalates, and dioxetanes, and systematically summarize the design principles, sensing mechanisms, and bioimaging and therapeutic applications of representative chemiluminescent probes as well as theranostic agents. Finally, the potential challenges and perspectives of chemiluminescent platforms for bioimaging and therapeutics are also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据