期刊
MATERIALS CHEMISTRY AND PHYSICS
卷 255, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.matchemphys.2020.123557
关键词
Ti-Nb-Ta-Zr alloys; Mechanical properties; Structural properties; Physicochemical properties; Implantation
资金
- Ministry of Education and Science of Russia [RFMEFI60417X0196]
A technology for producing a new homogeneous Ti-20Nb-13Ta-5Zr alloy has been developed. It is shown that the alloy is single-phase with a beta-Ti type crystal lattice. The alloy has the required mechanical properties (tensile strength of about 745 MPa). On the surface of plates and wire made of alloy, a relief of micro- and nanoscale is observed. In terms of the ability to generate reactive oxygen species and long-lived reactive protein species, the Ti-20Nb-13Ta-5Zr alloy is more preferable than nitinol. It was established that cell cultures growing on plates or wire made of Ti-20Nb-13Ta-5Zr alloy had a significant mitotic index (2%). The number of viable cells was at least 95-96% of the overall cell count. According to the results of implantation of the alloy in the form of plates or wire ring to animals, it can be concluded that the alloy is biocompatible. The morphology of the surface of the samples did not change after biological experiments. It can be assumed that the alloy Ti-20Nb-13Ta-5Zr is a material potentially suitable for medical applications.
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