Hunting Down the HIV-1 Reservoir: A Starring Role for Antibodies?

The persistence of viruses hidden in a reservoir of latently infected CD4(+)T cells under antiretroviral therapy is the major obstacle to an HIV-1 cure. Recently published in Nature, two seminal studies from Descours et al. (2017) and Nishimura et al. (2017) bring hope for tracking and possibly eradicating the HIV-1 reservoir.