4.7 Article

Therapeutic iminoboronate-based polymersomes with a Cu(ii)-mediated Fenton reaction-enhanced ROS-response

期刊

CHEMICAL COMMUNICATIONS
卷 56, 期 81, 页码 12246-12249

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc03607b

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资金

  1. Nature Science Foundation of China [51803115, 81771972]
  2. Nature Science Foundation of Shaanxi Province [2019JQ-528]
  3. Fundamental Research Funds for the Central Universities [GK201801003, GK201802009, GK201901001, GK201803031]
  4. Program of Introducing Talents of Discipline to Universities [B14041]
  5. Natural Science Basic Research Plan in Shaanxi Province of China [2019KJXX-083]
  6. China Scholarship Council (CSC)
  7. Natural Sciences and Engineering Research Council of Canada (NSERC)
  8. le Fonds de Recherche du Quebec: Nature et Technologies (FRQNT)

向作者/读者索取更多资源

Reactive oxygen species (ROS)-responsive prodrug nanoplatforms may not work efficiently due to insufficient ROS concentrations, so therapeutic polymersomes of a metallisable triamine-centered iminoboronate-functionalized amphiphilic starlike prodrug (N-3-(OEG-IBCAPE)(4)) are prepared to show a Cu(ii)-mediated Fenton reaction-enhanced ROS response.

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