期刊
WATER RESEARCH
卷 186, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.watres.2020.116404
关键词
Wastewater-based epidemiology; Environmental monitoring; Coronavirus; SARS-CoV-2; COVID-19; Sewage
资金
- Xunta de Galicia (Spain) [2014-PG110]
- EPSRC IAA program (UK) [EP/R511584/1]
- Natural Environment Research Council's (UK) COVID-19 Urgency programme [NE/V004883/1]
- Centre of Expertise for Waters
- EPSRC [EP/R036705/1] Funding Source: UKRI
- NERC [NE/V004883/1, NE/V010441/1, NE/M010996/1, NE/M011577/1] Funding Source: UKRI
The presence of SARS-CoV-2 in the feces of infected patients and wastewater has drawn attention, not only to the possibility of fecal-oral transmission but also to the use of wastewater as an epidemiological tool. The COVID-19 pandemic has highlighted problems in evaluating the epidemiological scope of the disease using classical surveillance approaches, due to a lack of diagnostic capacity, and their application to only a small proportion of the population. As in previous pandemics, statistics, particularly the proportion of the population infected, are believed to be widely underestimated. Furthermore, analysis of only clinical samples cannot predict outbreaks in a timely manner or easily capture asymptomatic carriers. Threfore, community-scale surveillance, including wastewater-based epidemiology, can bridge the broader community and the clinic, becoming a valuable indirect epidemiological prediction tool for SARS-CoV-2 and other pandemic viruses. This article summarizes current knowledge and discusses the critical factors for implementing wastewater-based epidemiology of COVID-19. (c) 2020 The Authors. Published by Elsevier Ltd.
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