A functionalized carbon nanotube nanohybrids-based QuEChERS method for detection of pesticide residues in vegetables and fruits

A self-separating, analyte-compatible, and efficient clean-up method for QuEChERS extracts was designed and developed based on dispersive solid-phase extraction using a branched polyethylenimine and nanoscale CaSO4 functionalized carboxylated multi-walled carbon nanotubes (MWCNTs) nanohybrids as sorbent. The feasibility of using a self-separating strategy based on the functionalization of sorbent in a purification procedure was analyzed for the first time in this study. Compared to the traditional QuECh-ERS method, the proposed method is rapid and convenient without centrifugation of numerous samples in the clean-up process. The use of nanohybrids overcame the issue of low recoveries for planar pesticides, which are easily adsorbed using MWCNTs. A better clean-up capability of the nanohybrids to remove matrix interferences and reduce matrix effect was demonstrated compared with that of traditional clean-up sorbent primary secondary amine. The method was validated by determining twentyeight pesticides in cucumber, cabbage, apple, and orange. Limits of detections were in the range of 0.0001-0.0026 mg/kg. Spike recoveries of pesticides were within 75.3 - 113.6%, with relative standard deviations less than 14.3% at levels 0.01 mg/kg and 0.1 mg/kg. The developed method was successfully applied to monitor the multi-residues. (C) 2020 Published by Elsevier B.V.