期刊
CURRENT OPINION IN PHYSIOLOGY
卷 16, 期 -, 页码 1-7出版社
ELSEVIER
DOI: 10.1016/j.cophys.2020.03.003
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类别
资金
- Fight for Sight
- Royal College of Surgeons of Edinburgh
- National Institute for Health Research (NIHR)
- Biomedical Research Centres (BRC) at the Oxford University Hospitals NHS Foundation Trust
- Academy of Medical Sciences
- Wellcome Trust
Retinal degenerations account for the majority of untreatable causes of blindness. Advances in gene delivery vectors, CRISPR/Cas9-based gene editing systems, and electronic engineering have led to a wide range of strategies for correcting visual loss. Here, we provide an overview of retinal gene therapy, gene editing, optogenetics and retinal prostheses using examples from recent clinical trials and pre-clinical studies.
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