3.8 Review

Adiponectin and insulin: molecular mechanisms of metabolic disorders

期刊

BYULLETEN SIBIRSKOY MEDITSINY
卷 19, 期 3, 页码 188-197

出版社

SIBERIAN STATE MEDICAL UNIV
DOI: 10.20538/1682-0363-2020-3-188-197

关键词

adiponectin; insulin; adipocytes; obesity

向作者/读者索取更多资源

Adiponectin, the most common plasma adipocytokine, plays a crucial metabolic and anti-inflammatory role. With insulin resistance associated with obesity, an increase of adiponectin concentration, which leads to the activation of signaling pathways involved in the regulation of metabolism, occurs. Currently, adiponectin is being investigated as a potential therapeutic target for metabolic syndrome, although more research is required to understand the underlying mechanisms controlling its levels. In this review, we will examine the main mechanisms that control adiponectin levels in blood serum and its role in insulin-sensitizing effect, as well as evaluate the potential use of adiponectin and its receptors as a potential therapeutic target.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

3.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据