期刊
FRONTIERS IN CHEMISTRY
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fchem.2020.585077
关键词
multi-responsibility; drug delivery; silk fibroin; nanoparticle; β -sheet
资金
- National Natural Science Foundation of China [82072060]
- Fundamental Research Funds for the Central Universities [XDJK2019TY002]
- Venture and Innovation Support Program for Chongqing Overseas Returnees [cx2018029]
Silk fibroin has the merits of biocompatibility, biodegradability, ease of processing, and feasibility of modification, which present it as a promising drug delivery material. This review focuses on the structures of silk fibroin, the controlled transformation of secondary structures, and the formation mechanism of silk fibroin-based nanoparticles (SFNPs). We also discuss the intrinsic multi-responsive, surface functionalization, and transgenic modification of SFNPs for drug delivery.
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