SARS-CoV-2 Viral Load on Admission Is Associated With 30-Day Mortality

A study of 181 individuals from a single community hospital found SARS-CoV-2 viral load on admission was associated with a significantly increased 30-day mortality (OR 4.20 [95% CI: 1.62-10.86]), and anti-SARS-CoV-2 IgG seropositivity on admission trended toward a reduced 30-day mortality (OR 0.43 [95% CI: 0.15-1.26]). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load on admission was associated with a significantly increased 30-day mortality (odds ratio [OR], 4.20; 95% CI, 1.62-10.86), and anti-SARS-CoV-2 nucleocapisid IgG seropositivity on admission trended toward a reduced 30-day mortality (OR, 0.43; 95% CI, 0.15-1.26). Reporting of quantitative SARS-CoV-2 viral load and serologic assays may offer prognostic clinical information.