期刊
MEDCOMM
卷 1, 期 3, 页码 270-301出版社
WILEY
DOI: 10.1002/mco2.26
关键词
clinical treatments; COVID-19; human coronaviruses; MERS; SARS
资金
- National Major Scientific and Technological Special Project [2018ZX09733001]
- Development ProgramofChina [2016YFA0201402]
- Excellent Youth Foundation of Sichuan Scientific Committee Grant in China [2019JDJQ008]
Coronaviruses (CoVs), a subfamily of coronavirinae, are a panel of single-stranded RNA virus. Human coronavirus (HCoV) strains (HCoV-229E, HCoV-OC43, HCoV-HKU1, HCoV-NL63) usually cause mild upper respiratory diseases and are believed to be harmless. However, other HCoVs, associated with severe acute respiratory syndrome, Middle East respiratory syndrome, and COVID-19, have been identified as important pathogens due to their potent infectivity and lethality worldwide. Moreover, currently, no effective antiviral drugs treatments are available so far. In this review, we summarize the biological characters of HCoVs, their association with human diseases, and current therapeutic options for the three severe HCoVs. We also highlight the discussion about novel treatment strategies for HCoVs infections.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据