期刊
CURRENT OPINION IN SYSTEMS BIOLOGY
卷 24, 期 -, 页码 86-92出版社
ELSEVIER
DOI: 10.1016/j.coisb.2020.10.003
关键词
Antibody repertoire sequencing; Immune receptor genes; AIRR-seq tools; Rep-seq tools
Tools for adaptive immune receptor repertoire (AIRR) sequencing continue to evolve rapidly, and, although some established frameworks are emerging, there are no complete solutions: it is necessary to select tools and build a customised pipeline. Emerging trends of interest include standards for data interchange, tools for single-cell sequencing, genotyping, and tools that make use of probabilistic and structural inferences to identify receptor sequences of interest.
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