期刊
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
卷 25, 期 9, 页码 1605-1611出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TNSRE.2017.2682923
关键词
Ultrasound neurostimulation; noninvasive stimulation; ultrasound retinal prosthesis (USRP); contact-lens shape array; multiple-focus neurostimulation
资金
- National Science Foundation Grants of China [61302038, 11325420, 81527901, 61571431, 11272329, 11574342, 11534013]
- National Basic Research Program of China [2015CB755500]
- Research Project of CAS [YZ01507, QYZDB-SSW-JSC018]
- Guangdong Innovative and Entrepreneurial Research Team Program [2013S046]
- Natural Science Foundation of Guangdong Province [2015A030306018, 2014A030313686, 2014A030312006]
- Shenzhen Peacock Plan [20130409162728468]
- Shenzhen International Collaboration [GJHZ20140417113430615]
- Foundation Grants of Shenzhen [JCYJ20140610151856707]
Millions of people around the world suffer from varying degrees of vision loss (including complete blindness) because of retinal degenerative diseases. Artificial retinal prosthesis, which is usually based on electrical neurostimulation, is the most advanced technology for different types of retinal degeneration. However, this technology involves placing a device into the eyeball, and such a highly invasive procedure is inevitably highly risk and expensive. Ultrasound has been demonstrated to be a promising technology for noninvasive neurostimulation, making it possible to stimulate the retina and induce action potentials similar to those elicited by light stimulation. However, the technology of ultrasound retinal stimulation still requires considerable developments before it could be applied clinically. This paper proposes a novel contact-lens array transducer for use in an ultrasound retinal prosthesis (USRP). The trans-ducer was designed in the shape of a contact lens so as to facilitate acoustic coupling with the eye liquid. The key parameters of the ultrasound transducer were simulated, and results are presented that indicate the achievement of 2-D pattern generation and that the proposed contact-lens array is suitable for multiple-focus neurostimulation, and can be used in a USRP.
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