期刊
JOURNAL OF BIOTECHNOLOGY
卷 323, 期 -, 页码 9-16出版社
ELSEVIER
DOI: 10.1016/j.jbiotec.2020.07.017
关键词
Lactic acid; Bacillus coagulans; Lignocellulosic hydrolysates; Lignocellulosic inhibitors; Biodetoxification
资金
- Spanish Ministry of Economy and Competitiveness (MINECO) via the BIO_LIGWASTE project [RTC-2016-5281-5]
- Community of Madrid [S2018/BAA-4532]
Cellulose valorisation has been successfully addressed for years. However, the use of hemicellulosic hydrolysates is limited due to the presence of C5-sugars and inhibitors formed during pretreatment. Bacillus coagulans is one of the few bacteria able to utilize both C6- and C5-sugars to produce L-lactic acid, but its susceptibility to the lignocellulosic inhibitors needs further investigation. For such a purpose, the tolerance of different B. coagulans strains to increasing concentrations of inhibitors is studied. The isolated A162 strain reached the highest L-lactic acid productivity in all cases (up to 2.4 g L-1 h(-1)), even in presence of 5 g L-1 of furans and phenols. Remarkably, most of furans and phenolic aldehydes were removed from defined media and hemicellulosic gardening hydrolysate after fermentation with A162. Considering the high productivities and the biodetoxifying effect attained, A162 could be pointed out as a great candidate for valorisation of mixed sugars from hemicellulosic hydrolysates with high inhibitors concentration, promoting the implementation of lignocellulosic biorefineries.
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