期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 8, 期 44, 页码 10023-10049出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0tb01534b
关键词
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资金
- National Key R&D Program of China [2017YFC1104703]
- Fund of Key Laboratory of Advanced Materials of Ministry of Education [2020AML10]
- Sichuan Science and Technology Program [2019JDRC0020]
- 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University [ZYJC18002]
- International Joint Research Center of Aerospace Biotechnology and Medical Engineering, Ministry of Science and Technology of China
- 111 Project [B13003]
Decellularized materials (DMs) are attracting more and more attention because of their native structures, comparatively high bioactivity, low immunogenicity and good biodegradability, which are difficult to be imitated by synthetic materials. Recently, DMs have been demonstrated to possess great potential to overcome the disadvantages of autografts and have become a kind of promising material for tissue engineering. In this systematic review, we aimed to not only provide a quick access for understanding DMs, but also bring new ideas to utilize them more appropriately in tissue engineering. Firstly, the preparation of DMs was introduced. Then, the updated applications of DMs derived from different tissues and organs in tissue engineering were comprehensively summarized. In particular, their advantages, drawbacks and current improvements were emphasized. Moreover, we analyzed and proposed future perspectives.
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