3.8 Article

Germline BRCA1 mutated esophageal squamous cell carcinoma

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RARE TUMORS
卷 12, 期 -, 页码 -

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SAGE PUBLICATIONS LTD
DOI: 10.1177/2036361320972218

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BRCA mutation; BRCA1 mutation; esophageal cancer; squamous esophageal cancer

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The most common associated malignancies with BRCA mutations include breast and ovarian cancers. Less common malignancies associated with BRCA mutation include: pancreatic, prostate, colon, gastric, and biliary cancers. Esophageal cancer, particularly squamous cell carcinoma, has rarely been reported to harbor BRCA mutations. Here we report, to our knowledge, the first case of germline BRCA1 mutated associated esophageal squamous cell carcinoma.

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