A review on the synthesis of graft copolymers of chitosan and their potential applications

Chitosan is an antimicrobial, biodegradable and biocompatible natural polymer, commercially derived from the partial deacetylation of chitin. Currently modified chitosan has occupied a major part of scientific research. Modified chitosan has excellent biotic characteristics like biodegradation, antibacterial, immunological, metal-binding and metal adsorption capacity and wound-healing ability. Chitosan is an excellent candidate for drug delivery, food packaging and wastewater treatment and is also used as a supporting object for cell culture, gene delivery and tissue engineering. Modification of pure chitosan via grafting improves the native properties of chitosan. Chitosan grafted copolymers exhibit high significance and are extensively used in numerous fields. In this review, modifications of chitosan through several graft copolymerization techniques such as free radical, radiation, and enzymatic were reported and the properties of grafted chitosan were discussed. This review also discussed the applications of grafted chitosan in the fields of drug delivery, food packaging, antimicrobial, and metal adsorption as well as dye removal. (C) 2020 Published by Elsevier B.V.