期刊
EUROPEAN NEUROLOGY
卷 83, 期 3, 页码 235-241出版社
KARGER
DOI: 10.1159/000509268
关键词
Mesenchymal stem cells; Neurodegenerative diseases; Mechanism; Clinical treatment
资金
- National Natural Science Foundation of China [31570994]
- Natural Science Foundation of Zhejiang Province [LY15C100001]
Neurodegenerative disease is a kind of chronic, progressive nervous system disease characterized by neuron degeneration or apoptosis. Current treatments cannot prevent the development of the disease. Possible alternative treatments include cell therapy, especially with the use of mesenchymal stem cells (MSCs). MSCs are pluripotent stem cells with capacities for self-renewal and multidirectional differentiation. MSCs may serve as a reliable source of neural cells for potential cell replacement therapy or regenerative medicine treatment. Here, we summarized the therapeutic mechanisms of MSCs and how they can contribute to the development of treatments for neurodegenerative diseases.
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