期刊
RSC ADVANCES
卷 10, 期 63, 页码 38281-38286出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ra06564a
关键词
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资金
- National Natural Science Foundation of China [21602181, 21702171]
- China Postdoctoral Science Foundation [2016M602628]
Peroxynitrite (ONOO-) is a potent biological oxidant that plays a significant role in diverse physiological and pathological processes. A novel fluorescent probe HCA-OH was developed for specific and sensitive detection of peroxynitrite, and displayed a significant fluorescence turn-on signal. With low cytotoxicity and good photostability, the probe HCA-OH could be applied in imaging ONOO- distribution in HepG2 cells and live C. elegans in real time. Therefore, the probe can be a promising tool for imaging in vivo.
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