Racial Disparities in the Utilization and Outcomes of Transcatheter Mitral Valve Repair: Insights From a National Database

Background: There is paucity of data on racial disparities in the utilization and outcomes of transcatheter mitral valve repair (TMVR). Methods: We queried the National inpatient Sample database (2012-2016) for TMVR hospitalizations among Caucasian and African American patients. We conducted a propensity score matching analysis to compare outcomes of Caucasians versus African Americans. The main study outcome was in-hospital mortality. Results: Among 7940 TMVR procedures performed, 680 (8.6%) were performed in African Americans. TMVR was increasingly performed for both Caucasians and African Americans (P-trend = 0.01), although the proportion of African Americans did not change significantly over time (P-trend = 0.45). Compared to African Americans, Caucasians undergoing TMVR were significantly older (77.7 +/- 10.8 vs. 67.2 +/- 14.28, p < .001) and less likely to be women (45.3% vs.60.3%, p <.001). Caucasians undergoing TMVR had a higher in-hospital mortality compared with African Americans before matching (2.5% vs. 1.5%, odds ratio [OR] 1.75; 95% confidence interval [CI] 1.17:2.63, p =.01) as well as after matching (4.7% vs. 1.6%, OR 3.10; 95% CI 1.61:5.97, p < .001). Caucasians had higher in-hospital cardiac arrest and pacemaker insertion and shorter median length of stay. There was no difference in the incidence of other in-hospital outcomes between Caucasians and African Americans. Conclusion: This nationwide observational analysis showed a steady increase in number of TMVRs among Caucasians and African Americans. TMVRwas performed in a select cohort of African Americans who were significantly younger and more likely to be women compared with Caucasians. Caucasians undergoing TMVR had higher inhospital mortality compared with African Americans. Further research is needed to explore the reasons behind the racial disparities in the utilization and outcomes of TMVR. Published by Elsevier Inc.