期刊
TOXICOLOGY REPORTS
卷 7, 期 -, 页码 335-344出版社
ELSEVIER
DOI: 10.1016/j.toxrep.2020.02.002
关键词
Cell index; Impedance; Microsensor electrodes; Tetrazolium salts; RTCA
类别
资金
- Medical University of Gdansk
Real-time cell analysis (RTCA) is a technique based on impedance and microsensor electrodes. RTCA system allows label-free, real-time, and continuous monitoring of cell adhesion, morphology, and rate of cell proliferation. The system offers a wide range of applications, mainly in toxicological studies, new drug screening, and microbiology. Here, we describe the usefulness of the system in different applications and compare this technology with conventional endpoint assays based on tetrazolium salts. We present advantages and disadvantages of the system and endpoint methods and their limitations in cytotoxicity investigations.
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