期刊
FAMILY PRACTICE
卷 37, 期 3, 页码 321-324出版社
OXFORD UNIV PRESS
DOI: 10.1093/fampra/cmz078
关键词
Biopsy; colonoscopy; colorectal neoplasms; early detection of cancer; Mexico; occult blood
资金
- National Cancer Institute [1P20CA210286-01]
- UCSF Open Access Publishing Fund
Background: In middle-income countries, the burden of colorectal cancer (CRC) is increasing in parallel with resources for diagnosis and treatment. There is a potential benefit of CRC screening programs in Mexico. Objective: Since there are no organized screening programs in the country, we explored the willingness of individuals to complete a faecal immunochemical testing (FIT) based CRC screening program and its potential benefit in Mexico. Methods: We conducted a CRC screening program pilot in Veracruz, Mexico, during 2015-16 using FIT. Individuals with FIT results >100 ng of haemoglobin/ml buffer were referred for diagnostic colonoscopy. Results: Of 473 FIT kits distributed to adults aged 50-75, 85.8% (406) were completed by participants and analysed in the laboratory. Of these, 5.9% (24/406) of test results showed >100 ng haemoglobin/ml.Twenty-one participants completed colonoscopy.The positive predictive value of FIT >100 ng haemoglobin/ml for premalignant lesions was 33%. Conclusion: These results provide preliminary evidence of the willingness of individuals to complete FIT-based CRC screening program in Mexico. However, further evaluation of health systems resources will be needed prior to large-scale implementation of CRC screening programs.
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