Maculine: a furoquinoline alkaloid from the family Rutaceae: sources, syntheses and biological activities

Maculine is one of the furoquinolines which are characteristic of the family Rutaceae. Its chemical name is 9-methoxy[1,3]dioxolo[4,5-g]furo[2,3-b]quinoline and it was isolated from several genera of Rutaceae. The present mini-review covers the different sources of maculine, its methods of separation, synthetic pathways and biological activities. [GRAPHICS]