相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis
Zhang-Yu Zou et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)
Functional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice
Alessia Mirra et al.
SCIENTIFIC REPORTS (2017)
Early Synaptic Dysfunction in Parkinson's Disease: Insights From Animal Models
Tommaso Schirinzi et al.
MOVEMENT DISORDERS (2016)
ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
Aarti Sharma et al.
NATURE COMMUNICATIONS (2016)
Neuromuscular Junctions as Key Contributors and Therapeutic Targets in Spinal Muscular Atrophy
Marina Boido et al.
FRONTIERS IN NEUROANATOMY (2016)
Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis
Riccardo Ruffoli et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization
Tsuyoshi Udagawa et al.
NATURE COMMUNICATIONS (2015)
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP
Shuying Sun et al.
NATURE COMMUNICATIONS (2015)
FUS Interacts with HSP60 to Promote Mitochondrial Damage
Jianwen Deng et al.
PLOS GENETICS (2015)
ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation
Andrew King et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models
Jordi Magrane et al.
HUMAN MOLECULAR GENETICS (2014)
The ALS gene FUS regulates synaptic transmission at the Drosophila neuromuscular junction
James B. Machamer et al.
HUMAN MOLECULAR GENETICS (2014)
Activity-dependent FUS dysregulation disrupts synaptic homeostasis
Chantelle F. Sephton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
Jacqueline C. Mitchell et al.
ACTA NEUROPATHOLOGICA (2013)
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
Danielle C. Diaper et al.
HUMAN MOLECULAR GENETICS (2013)
Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS
Gary A. B. Armstrong et al.
HUMAN MOLECULAR GENETICS (2013)
ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN
Ewout J. N. Groen et al.
HUMAN MOLECULAR GENETICS (2013)
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules
Caroline Vance et al.
HUMAN MOLECULAR GENETICS (2013)
Mutations in the 3′ untranslated region of FUS causing FUS overexpression are associated with amyotrophic lateral sclerosis
Mario Sabatelli et al.
HUMAN MOLECULAR GENETICS (2013)
The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules
Kyota Yasuda et al.
JOURNAL OF CELL BIOLOGY (2013)
Calcium Channel Agonists Protect against Neuromuscular Dysfunction in a Genetic Model of TDP-43 Mutation in ALS
Gary A. B. Armstrong et al.
JOURNAL OF NEUROSCIENCE (2013)
Defects in Synapse Structure and Function Precede Motor Neuron Degeneration in Drosophila Models of FUS-Related ALS
Mohammad Shahidullah et al.
JOURNAL OF NEUROSCIENCE (2013)
Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
Philippe A. Parone et al.
JOURNAL OF NEUROSCIENCE (2013)
Mitochondria, motor neurons and aging
M. L. Garcia et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2013)
Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease
T. H. Gillingwater et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)
SYNAPTIC CHANGES IN ALZHEIMER'S DISEASE AND ITS MODELS
J. Pozueta et al.
NEUROSCIENCE (2013)
Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset
Mariana C. Rocha et al.
PLOS ONE (2013)
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2
Jacob C. Schwartz et al.
GENES & DEVELOPMENT (2012)
Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
Miranda L. Tradewell et al.
HUMAN MOLECULAR GENETICS (2012)
Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats
Cao Huang et al.
HUMAN MOLECULAR GENETICS (2012)
Mitochondrial Dynamics and Bioenergetic Dysfunction Is Associated with Synaptic Alterations in Mutant SOD1 Motor Neurons
Jordi Magrane et al.
JOURNAL OF NEUROSCIENCE (2012)
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS
Ruohan Xia et al.
MOLECULAR NEURODEGENERATION (2012)
FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations
Manuela Neumann et al.
BRAIN (2011)
FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth
Greg N. Brooke et al.
CANCER RESEARCH (2011)
The Dying-Back Phenomenon of Motor Neurons in ALS
Michal Dadon-Nachum et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
Cao Huang et al.
PLOS GENETICS (2011)
Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy
Kazuo Fushimi et al.
PROTEIN & CELL (2011)
Mitochondrial dysfunction in amyotrophic lateral sclerosis
Ping Shi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Extensive FUS-Immunoreactive Pathology in Juvenile Amyotrophic Lateral Sclerosis with Basophilic Inclusions
Eric J. Huang et al.
BRAIN PATHOLOGY (2010)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann et al.
EMBO JOURNAL (2010)
Mitochondrial Dysfunction is a Converging Point of Multiple Pathological Pathways in Amyotrophic Lateral Sclerosis
Ping Shi et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
Ya-Fei Xu et al.
JOURNAL OF NEUROSCIENCE (2010)
RNA processing pathways in amyotrophic lateral sclerosis
Marka van Blitterswijk et al.
NEUROGENETICS (2010)
Review: Neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy
L. M. Murray et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2010)
Deficits in axonal transport precede ALS symptoms in vivo
Lynsey G. Bilsland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
Xiu Shan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
Caroline Vance et al.
SCIENCE (2009)
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
T. J. Kwiatkowski et al.
SCIENCE (2009)
Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy
Shingo Kariya et al.
HUMAN MOLECULAR GENETICS (2008)
TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines
R Fujii et al.
JOURNAL OF CELL SCIENCE (2005)
Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: exclusion from the nucleus and accumulation in dendritic granules and spine heads
A Belly et al.
NEUROSCIENCE LETTERS (2005)
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology
R Fujii et al.
CURRENT BIOLOGY (2005)
Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man
LR Fischer et al.
EXPERIMENTAL NEUROLOGY (2004)
The Microprocessor complex mediates the genesis of microRNAs
RI Gregory et al.
NATURE (2004)
Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity
C Bendotti et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2001)