期刊
COSMETICS
卷 7, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/cosmetics7040083
关键词
nanostructured lipid carrier (NLC); Ficus deltoidea; virgin coconut oil; characterization; stability; antioxidant
资金
- Ministry of Education Malaysia, Prototype Research Grant Scheme [R.J13000.7846.4L656]
- Ministry of Education Malaysia, HiCoE [RJ13000.7856.4J266]
- Ministry of Education Malaysia, Fundamental Research Grant Scheme [RJ1300.7809.4F614]
In this study, the Ficus deltoidea extract loaded nanostructured lipid carrier was prepared by using the melt emulsification homogenization method. Virgin coconut oil is used as liquid lipid, while glyceryl monostearate is the solid lipid. Particle size, zeta potential, entrapment efficiency, drug loading and morphology of the obtained nanostructured lipid carrier (NLC) were measured. The size of the nanostructured lipid carrier incorporated with Ficus deltoidea (FDNLC) is 158.0 +/- 1.3 nm, with a polydispersity index of 0.15 +/- 0.02. The zeta potential obtained is 42.3 +/- 1.5 mV. The encapsulation efficiency and active ingredient loading capacity for FDNLC is 87.4% +/- 1.3% and 8.5% +/- 1.2%, respectively. The shape of FDNLC is almost spherical and the stability assessment showed that the obtained formulation is at least stable for 40 days. When compared with the positive controls, which are Trolox and ascorbic acid, FDNLC shows the highest antioxidant value. Cell proliferation activity study indicates that FDNLC is not toxic to cells, and FDNLC could potentially treat damage by ultraviolet B (UVB) irradiation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据