期刊
HETEROCYCLIC COMMUNICATIONS
卷 23, 期 1, 页码 43-54出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/hc-2016-0125
关键词
antimicrobial activity; conazole; Mannich base; microwave; piperazine
资金
- Scientific and Technological Research Council of Turkey (TUBITAK) [113Z181]
- Karadeniz Technical University, BAP, Turkey [8623]
The hydrazide 5, that was obtained from -1-(4-fluorophenyl) piperazine (1), was converted to the cor-responding carbothioamides 6a-c by the reaction with alkyl(aryl) isothiocyanates. The synthesis of conazole analogs 10a-f was performed via the intermediary of triazoles 7a-c. The condensation of triazoles 7a-c with -several -heterocyclic amines in the presence of formalde-hyde afforded the corresponding N-aminoalkylated tria-zoles 11-14. The effect of different catalysts and solvents on conventional and microwave (MW)-prompted reac-tions was examined. The synthesized compounds were screened for their antimicrobial activities.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据