期刊
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
卷 46, 期 3, 页码 213-223出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10408347.2015.1045119
关键词
Fiber optic biosensor; localized surface plasmon resonance (LSPR); probe geometry; surface plasmons
资金
- National Natural Science Foundation of China: Investigation of Fast Pathogen Detection Based on Novel Macroporous Chips Technology [21275105]
- National Recruitment Program of Global Experts (NRPGE)
- Hundred Talents Program of Sichuan Province (HTPSP)
- Sichuan University
Fiber optic-based biosensors with surface plasmon resonance (SPR) technology are advanced label-free optical biosensing methods. They have brought tremendous progress in the sensing of various chemical and biological species. This review summarizes four sensing configurations (prism, grating, waveguide, and fiber optic) with two ways, attenuated total reflection (ATR) and diffraction, to excite the surface plasmons. Meanwhile, the designs of different probes (U-bent, tapered, and other probes) are also described. Finally, four major types of biosensors, immunosensor, DNA biosensor, enzyme biosensor, and living cell biosensor, are discussed in detail for their sensing principles and applications. Future prospects of fiber optic-based SPR sensor technology are discussed.
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