期刊
HEARING RESEARCH
卷 352, 期 -, 页码 12-22出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.heares.2016.10.015
关键词
Tonotopic maps; Driven and spontaneous firing rate; Central gain; Single units; Local field potentials; Animal; Human; Tinnitus
资金
- Natural Sciences and Engineering Research Council of Canada (NSERC)
It is known that hearing loss induces plastic changes in the brain, causing loudness recruitment and hyperacusis, increased spontaneous firing rates and neural synchrony, reorganizations of the cortical tonotopic maps, and tinnitus. Much less in known about the central effects of exposure to sounds that cause a temporary hearing loss, affect the ribbon synapses in the inner hair cells, and cause a loss of high threshold auditory nerve fibers. In contrast there is a wealth of information about central effects of long duration sound exposures at levels <80 dB SPL that do not even cause a temporary hearing loss. The central effects for these moderate level exposures described in this review include changes in central gain, increased spontaneous firing rates and neural synchrony, and reorganization of the cortical tonotopic map. A putative mechanism is outlined, and the effect of the acoustic environment during the recovery process is illustrated. Parallels are drawn with hearing problems in humans with long-duration exposures to occupational noise but with clinical normal hearing. (C) 2016 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据