期刊
BMJ CASE REPORTS
卷 13, 期 9, 页码 -出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/bcr-2020-238597
关键词
radiology (diagnostics); infections; paediatrics (drugs and medicines); neurology (drugs and medicines); global health
We herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous thrombosis. Both conditions induce a proinflammatory cytokine drive resulting, among others, in a prothrombotic state. The disruption of the coagulation system in this case was supported by elevated D-dimers, fibrinogen and ferritin levels, consistent with thrombotic complications reported in some adult patients infected with COVID-19. The child also exhibited prolonged viral shedding that suggests severe disease.
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